Calcium is quickly absorbed and reaches bone mass thanks to vitamins D3 and K2, which also prevent vascular calcification. Maintaining the health of your heart and bones. K2 governs regular blood clotting, whereas D3 promotes a healthy immune system and muscle performance. K2 (MK-7) stimulates the protein osteocalcin, which integrates calcium into bone, while vitamin D3 ensures that calcium is easily absorbed. Calcium cannot function properly without D3 and K2. Matrix GLA protein (MGP) is activated by vitamin K2 (MK-7) to bind excess calcium and improve arterial flow and flexibility.

Immune System Control

According to recent research, regulating vitamin D blood levels could provide a solution method that promises a significantly lower fatality rate while also addressing the public health problem of vitamin D shortage in general. To avoid long-term health hazards, vitamin K2 and magnesium should be given alongside D3. Vitamin D3 with K2 is an immune-regulating hormone that can be considered harmless.

Absorption of Calcium

The simplest way to avoid deficiencies is to take D3 supplements orally. One common argument against vitamin D3 supplementation is that increasing intake could lead to vitamin D toxicity, often known as hypervitaminosis D. Hypercalcemia, or the accumulation of calcium in the blood, can lead to vascular calcification, osteoporosis, and kidney stones. However, it has been suggested that hypercalcemia is caused by a vitamin K2 shortage, because K2 carboxylates the bone gamma-carboxyglutamic acid-containing protein (osteocalcin). Non-activated osteocalcin reduces calcium absorption by the bones, whereas activated osteocalcin deposits calcium in the bones. Higher 25(OH)D serum levels increase the rate of osteocalcin production, hence K2 is needed as a natural antagonist.

One of the fastest-growing and most successful product pairings is Core Vitamins D3 and K2. Based on the specific benefits of each vitamin in mediating calcium, the D3 and K2 mixture has been progressively rising in popularity around the world. Vitamins D3 and K2 are both vital nutrients that must be consumed throughout one’s life. Vitamin D3 and K2 were shown to be two of the few essential vitamins that are typically deficient in children’s diets.

Health of the Bones

By activating two proteins that balance calcium in the body, vitamin K2 improves bone and heart health. The improved form of K2, K2 MK-7, stimulates the osteocalcin proteins that help bones absorb calcium. Meanwhile, vitamin D3 helps the body absorb calcium and has been linked to a lower risk of breast cancer.

Protease activation

The novel pairing’s success is likely due to an increasing body of D3 and K2 research, which includes a meta-analysis on D3 and vitamin K synergy and bone health released in March of this year. While bone studies generally focus on D3 and K2 synergy on osteocalcin protein expression and activation, cardiovascular D3 and K2 studies reveal enhanced expression and activation of matrix Gla protein, which has been proven to have a role in preventing arterial calcification.

While the D3 and K2 combination is the most important aspect in the pairing’s bio-efficiency, a variety of dose formats are available. In fact, by adding K2, any existing vitamin D3 product, independent of dose format, can be improved.


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